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Contacts

Department of Animal, Veterinary & Food Sciences

Physical Address:
E. J. Iddings Agricultural Science Laboratory, Rm 213
606 S Rayburn St

Mailing Address:
875 Perimeter Drive MS 2330
Moscow, ID 83844-2330

Phone: 208-885-6345

Fax: 208-885-6420

Email: avs@uidaho.edu

Web: uidaho.edu/cals/avs

Directions

Mailing Address:
16 Hot Springs Ranch Road
Carmen, ID 83462

Phone: 208-756-2749

Web: uidaho.edu/cals/nmcreec

Directions

Mailing Address:
University of Idaho
1908 E. Chicago Street
Caldwell, ID 83605

Phone: 208-795-5331

Email: baumhoff@uidaho.edu

Web: uidaho.edu/cals/food-technology

Location

Daniel Fitzsimons

Daniel Fitzsimons

Assistant Professor

Office

Ag Biotech, Room 307

Phone

208-885-5054

Mailing Address

Animal, Veterinary and Food Sciences
University of Idaho
875 Perimeter Drive MS 2330
Moscow, ID 83844-2330

My research focuses on identifying the molecular processes that underlie the regulation of cardiac contraction and relaxation in the context of normal and diseased states, such as hypertrophic cardiomyopathy and heart failure.

Ph.D., University of California, Irvine, 1989
B.S., University of California, Irvine, 1983

  • To more fully understand how calcium and signal transduction pathways (e.g., β-AR) modulate ventricular function on a beat-to-beat basis.
  • To ascertain the roles of specific contractile and regulatory proteins in modulating myocardial contractility through the generation of unique murine CRISPR models that simulate the diseased state in human myocardium.
  • To utilize a translational approach in studying the pathophysiology of heart disease in mammalian myocardium.
  • To define the mechanisms of depressed myocardial contractility associated with right-sided congestive heart failure (brisket disease) in cattle.

  • Gregorich ZR, JR Patel, W Cai, Z Lin, R Heurer, DP Fitzsimons, RL Moss, and Y Ge. (2019). Deletion of enigma homologue from the Z-disc slows tension development kinetics in mouse myocardium. J. Gen. Physiol. 151:670-679. PMCID: PMC6504290.
  • Giles J, JR Patel, A Miller, E Iverson, D Fitzsimons, and RL Moss. (2018). Recovery of left ventricular function following in vivo re-expression of cardiac myosin binding protein C. J. Gen Physiol. 151:77-89. PMCID: PMC6314388.
  • Moss RL, TL Lynch, and DP Fitzsimons. (2017). Acting on an impulse (or two or three): adaptive advantage of a high-frequency burst of action potentials at the onset of tetany in fast-twitch skeletal muscle fibers. J Gen Physiol. 149:297-300. PMCID: PMC5339515.
  • Rosas PC, Y Liu, MI Abdalla, CM Thomas, DT Kidwell, GF Dusio, D Mukhopadhyay, R Kumar, KM Baker, BM Mitchell, PA Powers, DP Fitzsimons, BG Patel, CM Warren, RJ Solaro, RL Moss, and CW Tong. (2016). Phosphorylation of cardiac myosin-binding protein-C is a critical mediator of diastolic function. Circ Heart Fail 8:582-594. PMCID: PMC4447128.
  • Moss RL, DP Fitzsimons, JC Ralphe. (2015). Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium. Circ Res 116:183-192. PMCID: PMC4283578.

Contacts

Department of Animal, Veterinary & Food Sciences

Physical Address:
E. J. Iddings Agricultural Science Laboratory, Rm 213
606 S Rayburn St

Mailing Address:
875 Perimeter Drive MS 2330
Moscow, ID 83844-2330

Phone: 208-885-6345

Fax: 208-885-6420

Email: avs@uidaho.edu

Web: uidaho.edu/cals/avs

Directions

Mailing Address:
16 Hot Springs Ranch Road
Carmen, ID 83462

Phone: 208-756-2749

Web: uidaho.edu/cals/nmcreec

Directions

Mailing Address:
University of Idaho
1908 E. Chicago Street
Caldwell, ID 83605

Phone: 208-795-5331

Email: baumhoff@uidaho.edu

Web: uidaho.edu/cals/food-technology

Location